To support healthcare professionals in improving adherence, a series of articles has been developped to provide digestible learning resources around the role behavior science plays in adherence, including practical insights relating to therapy areas. The articles provide a useful companion to a series of masterclasses where the subjects of adherence and behavioral science are explored in more depth.


Latest articles

The role of beliefs in non-adherence

Beliefs have a strong influence over non-adherent behavior Adherence to medication can be influenced by a number of important beliefs that the patient holds, including their perception of their illness, their treatment, and self-efficacy (their own capacity to adhere).1 In the long term, adherence to medication requires individuals to initiate behavior based on:2 The Health…

Gastroenterology

Understanding the challenge of adherence in pancreatic exocrine insufficiency

Pancreatic exocrine insufficiency is associated with several conditions Pancreatic exocrine insufficiency (PEI) is defined by insufficient secretion or function of pancreatic enzymes or sodium bicarbonate for normal digestion.1,2 Its prevalence in the general population is unclear, and estimations are problematic due to the lack of a suitable screening test.1 It is, however, accepted that prevalence…

Gastroenterology

The adherence challenge in cardiovascular disease

Cardiovascular diseases have a social and economic impact Cardiovascular disease is the leading cause of mortality globally, accounting for 17.9 million deaths a year,1 with around 75-80% of these deaths taking place in low- and middle-income countries.2 For example, in Russia, cardiovascular disease is the leading cause of death in men aged 49 or older.3…

Cardio Metabolic

Understanding adherence from a cardiovascular-disease perspective

Key Messages Defining adherence Adherence is a key factor in the effectiveness of therapies for both chronic and acute diseases. This is particularly true for cardiovascular disease, where nonadherence to chronic medications can have a negative impact on both the patient and the healthcare system. Non- adherence is often dubbed the Achilles heel of evidence-based…

Cardio Metabolic

The role of beliefs in non-adherence

Beliefs have a strong influence over a patient’s motivation to adhere to treatment These include patient beliefs about their illness, their treatment and their own capacity for adhering (self-efficacy) It is vital that clinicians assess patients individually to understand their beliefs and motivations, supporting them in adhering to their medication regimens Beliefs have an important…

Cardio Metabolic

Using tools to assess patient adherence

Measures and survey tools are useful for characterizing patient health behavior Quantitative methods are useful for characterizing health behavior and supporting patients in the self-management of their conditions. Surveys and questionnaires have the advantages of being easy to implement at the point of care and being acceptable to patients.1 They provide explicit examples and information…

Cardio Metabolic

Personalization of adherence support with Patient Support Programs (PSPs): the advent of the digital era

PSPs are behavioral interventions for improving adherence Patient Support Programs, or PSPs, can range from simple calendar pill boxes or pill blister packaging, to organized programs based on behavioral science frameworks.1,2 They can either be provided directly by the physician’s office or via sponsored programs. They are designed to support patients in being comfortable with…

Cardio Metabolic

The impact of Patient Support Programs on adherence: enhancing engagement and improving effectiveness

Patient Support Programs are designed to boost adherence Patient Support Programs (PSPs) employ a variety of techniques to help patients follow their treatment and deal with their conditions.1 Some are purely informative and provide practical information to patients on topics such as disease management and drug management (especially for complex drugs), etc. The channels through…

Cardio Metabolic

How do PSPs impact adherence?

Non-adherence is a major issue that can be addressed by PSPs Non-adherence impedes patients from benefiting from the clinical promise of their treatment. Medications that have proven their potential in clinical trials may not deliver on that potential in the real world, potentially because of non-adherence.1 The numbers speak for themselves: average adherence rates for…

Central Nervous System

“Personalizing” adherence support with Patient Support Programs

Patient Support Programs are behavioral interventions for improving adherence Non-adherence to therapies in neurological conditions is a significant issue, associated with worse clinical outcomes and increased healthcare utilization and costs.1 There are many factors involved, including complexity of medication regimens, depression, gender, and duration of disease that may lead to a patient being non-adherent,2,3 therefore,…

Central Nervous System

Activating patients to improve adherence

Measures and survey tools are useful for characterizing patient health behavior Chronic diseases are a global public health issue and are increasing in prevalence and associated costs. These conditions require significant self-management by patients, including adherence to therapy regimens and medication.1 Adherence to epilepsy medication is associated with improved control of symptoms; however, non-adherence is…

Central Nervous System

The Behavior Change Wheel: A framework for improving adherence

Improving patient outcomes and adherence requires an actionable framework Previous articles in this series demonstrate that non-adherence is a significant public health issue in patients with neurologic disease. A study conducted in Europe in 2004 estimated that the annual economic cost of neurological disease (including dementia, epilepsy, migraine and other headaches, multiple sclerosis, Parkinson’s disease…

Central Nervous System

The Transtheoretical Model and the “stages” of patient adherence

The Transtheoretical Model: a tool for influencing positive behavioral change Neurological disorders are a significant public health issue worldwide.1 Non-adherence to therapy for these conditions results in poor response to therapy, impacts on the quality of life of patients and causes associated costs to them and healthcare systems.2,3 Non-adherence rates have been shown to be…

Central Nervous System

The Theory of Planned Behavior: A Patient’s Control Dilemma

How do people make difficult decisions? How do people decide which career to undertake, what car to buy, or whether to take medication? Important decisions are typically the result of some degree of thought and planning, a process that Daniel Kahneman labelled “System 2” thinking in his groundbreaking book, Thinking Fast and Slow.1 What is…

Central Nervous System

Understanding Patient Attitudes: The Health Belief Model

The Health Belief Model (HBM) is a model to help understand what patients believe about their health The HBM can be used to identify detrimental patient behaviors caused by a poor understanding of a condition or treatment The HBM can be used to structure interactions with patients to enhance their understanding of treatment and lifestyle…

Central Nervous System