What is this questionnaire?

The Pancreatic Exocrine Insufficiency Questionnaire (PEI-Q) is an 18-item Patient-Reported Outcome questionnaire designed to be completed by patients with pancreatic exocrine insufficiency (PEI) to assess their PEI symptoms and associated impact on health-related quality of life. A Patient-Reported Outcome is any report of the status of a patient’s health condition that comes directly from the patient, without interpretation by a clinician or anyone else.

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Why measure PEI symptoms and impacts using a questionnaire?

Currently there are no known Patient-Reported Outcome questionnaires that are specific to PEI. Due to the subjective nature of PEI symptoms (e.g. pain), they are best measured via patient self-report. A Patient-Reported Outcome questionnaire can be utilized in routine clinical practice to guide treatment decisions and monitor patients’ symptom severity, thus helping ensure patients’ symptoms are adequately controlled and aid patient-clinician communication.

What is the purpose of this questionnaire?

The purpose of this questionnaire is to quantify and potentially track changes in PEI symptoms and associated impact on health-related quality of life. In doing so, this questionnaire aims to:

  • Aid identification and diagnosis of PEI alongside other diagnostic tests and methods;
  • Assist in the management of patients already diagnosed with PEI, ensuring correct and optimum treatment dosage;
  • Monitor the impact of PEI on patients’ lives;
  • Facilitate patient-clinician communication.

Of note, this questionnaire is designed to complement and improve current best practice and inform discussions around treatment rather than replace standard clinical methods of diagnosing PEI and assessing PEI symptoms.

PEI-Q user manual

PEI-Q questionnaire was developed and validated by group of scientific authors as a patient-reported outcome instrument. Related publications: 1. Qualitative Assessment of the Symptoms and Impact of Pancreatic Exocrine Insufficiency (PEI) to Inform the Development of a Patient-Reported Outcome (PRO) Instrument. The patient. Mar 22 2017;10(5):615-628. 2. Johnson at al. Psychometric evaluation of a patient-reported outcome measure in pancreatic exocrine insufficiency (PEI). Pancreatology. 2019; 19: 182-190.

To protect the integrity of the instrument, the PEI-Q including the user manual, scoring algorithm and any versions or translations of the above, and all associated intellectual property rights, are owned by Abbott.